Shutter Island, the fourth Martin Scorsese film to showcase the talents of Leonardo DiCaprio, opens today. In this noirish thriller, Leonardo DiCaprio's character, Teddy, is a U.S. Marshall tasked with tracking down a disappeared, criminally insane mental patient. The plot unfolds within one very scary hospital, which also happens to be located on a remote island–one in the midst of a hurricane. Of course, things aren't quite what they seem, and it soon becomes clear that there could be more than one psycho on the loose. Rather than give away the ending, we've rounded up five of the best asylum escapes to grace the silver screen (above).